A Proposal Regarding Best Practices for Validating the Identity of Genetic Stocks and the Effects of Genetic Variants[OPEN]

A Proposal Regarding Best Practices for Validating the Identity of Genetic Stocks and the Effects of Genetic Variants.

Molecular Detection of Novel Genetic Variants Associated to Anaplasma ovis among Dromedary Camels in Iran

To the best of our knowledge, little information is available regarding the presence of Anaplasma species in camels in Iran. This study sought to investigate the presence of Anaplasma species by microscopy and polymerase chain reaction (PCR) assays in 100 healthy dromedaries (Camelus dromedarius) arriving for slaughter. The microscopic examination of Giemsa-stained blood films revealed that Ana...

NUDT15 genetic variants and 6-mercaptopurine intolerance in pediatric acute lymphoblastic leukemia: an updated review

Acute lymphoblastic leukemia (ALL) accounts for nearly 30% of pediatric cancers. The maintenance treatment for ALL comprises daily oral 6-mercaptopurine (6-MP) and weekly methotrexate (MTX). 6-MP is a purine analog that can significantly improve the long-term survival of ALL patients. Despite more than 90% of 5-year survival of childhood ALL in developed countries, treatment interruption due to...

Genetic characteristics of different populations of Litopenaeus vannamei in hatchery centers of Bushehr province

The aim of this study was identifying different populations and determining the genetic characteristics of three different sub-adult stocks of Litopenaeus vannamei in hatchery of Iran Shrimp Research Center by microsatellites DNA markers in Bushehr province during from October to November 2019. Up to 50 individuals were sampled per stock, with equal contribution by sex. The tissue preserved in ...

Genetic characterization of great sturgeon brood stocks- recommendations for the conservation management and aquaculture

The great sturgeon, Huso huso, is one of the most important cultured sturgeon species in Iran, which effective management of aquaculture production of this species requires knowledge of broodstock structure, mating patterns, and genetic diversity of broodstock. The aim of the present study was the application of microsatellite DNA analysis for genetic diversity assessment in the first generatio...